Identification of a direct interaction between interleukin 2 and the p64 interleukin 2 receptor gamma chain.
نویسندگان
چکیده
منابع مشابه
Identification of the functional interleukin-2 binding domain of the chicken common cytokine receptor gamma chain.
CD132 is the common gamma chain to a number of cytokine receptor complexes including that for IL-2. To identify the functional domain of chicken CD132 (chCD132), the cDNA of chCD132 was cloned, and a neutralizing monoclonal antibody, raised against a recombinant chCD132 protein, was identified by inhibition of IL-2-dependent proliferation of T cells. Flow cytometry analysis revealed that chCD13...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1993
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.90.6.2428